Commercial Hormone Replacement Therapy Jeopardized Proinflammatory Factors in Experimental Rat Models

نویسندگان

چکیده

BACKGROUND: Hormonal contraceptive therapy is considered the easiest and most convenient method. Commercially, available combination differs in their composition concentration of combined constituents. These variations make some these products preferred over others by consumers based on side effects profile. AIM: The objective current research was to ascertain proinflammatory influences commercially products. METHODS: To do so, five groups rats (ten each group) were exposed Microgynon, Depo-Provera, marvel on, Yasmin compared control non-treated group. We measured markers including d-dimer, TNF-α (tumor necrosis factor-alpha), IL (interleukin)-6, (interleukin)-1B, c-reactive protein. RESULTS: results confirmed that has induced deleterious indicated significant elevation IL1B. CONCLUSION: Hormone replacement should be critically precautions raised inpatient with subclinical diseases, especially cardiovascular ones.

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ژورنال

عنوان ژورنال: Open Access Macedonian Journal of Medical Sciences

سال: 2022

ISSN: ['1857-9655']

DOI: https://doi.org/10.3889/oamjms.2022.9924